Parasiticides



Patented Feh. M ESQ Con rm. {Elev 1 Delaware Application December as, 1932,,

The present invention refers to harasiticides which comprise organic compounds containing in theirmolecule'a straight carbon chainoi lZ carbon atoms, substituted particularly at least 5 at one of its and carbon atoms by a negative atom or a group containing such a negative atom, said carbon atom also carrying hydrogen. By negative atom we mean a non-metallic element included in grcujcs VIand War the periodic system of elements-in other words; thesubstltuents consistof or comprise ritrogen, phosphorous. oxygen, sulfur, selenium, itellu'rium d'r a halogen. I These derivatives of this straight vQha l li(lode-- cane (Cums) are all toxic to lowerii'oi'msfoiQife, particularly fungi, insects and more specifically soft bodied insects, and we attribute. this characteristic :toxicity to thehydrccarhozich "irre; spectlve ofjthesubstituents described'abovewhich afiect the'toxicity only in a g'radual'manrierc' Lauryl alcohol orv 'dodecanoljCl-BiCHi) 1103 has become hnically available For various thetic methods. it is quite eiiective for controlling soft jhodied such as aphids,

thrips, etc.

Lauryl amine and its substitution "products are similarly toxic insects and can he used as parasiticides.

Esters of lauryi alcohol with organic or in= organic acids, particularly those containing sulfur and/or nitrogen are even more effective as insecticides than the straight liaurqvl alcohol.

In the case of the esters of dior poly-basic acids with lauryl alcohol, we niai use the neutral esters but we prefer to use the partial esters so that the remaining acid grou s can he used for obtaining water solubility. radium law'yl sulfate, sodium di-lauryi phosphate, sodium lauryl xanthatasodium iauryl mercagatide, sodium lau-' ryl phthalate are examples of water soluble salts of partial lauryi esters which can he used in this manner.

The lauryl halogenids are regarded as esters of lauryl alcohol with hydrohalegcu acids. These esters as well as the esters of lauryi alcohol with mono-basic acids are substantially water insoluble. These, as well as other water insoluble lauryl derivatives. are best used in the form of aqueous emulsions in the presence of the usual emulsifying and spree agents, such as suiionatd vegetable, animal ormineral oil s soaps,

alkylated hydrocarbon'sulionic acidaetc. r 1 -We also found that the toxicity of the lauryl whic f ti dm muifl hPth u '9 Th s a sari ativ l n h erm abs-s e .lt rm x=orrasrr sen weir ons n" ea-Ten.

p ami -i ethers' as well as their sulfur; selenium and teIIurium-"a;na-

a "-'cyanide, suliate nitrate" 1;

oup persists in I a. ...r unib cr of other. derivatives elements-and 4. X=NR R where R and R may be hvdroso gen or an organic radical.

ryl alcohol with small amounts of the higher or lower hcmologs from ctyl to cetyl alcohol, but the insecticidal value of such mixtures of alcohol or corresponding derivatives is dependent primarily on the content of lauryl derivatives.

. crude alcohol. This product contains largely Iau 45 Among the large number of toxic lauryl derivatives exemplified above we cite the following which are of great merit for controlling insect some of the pests thriving on' vegetable life and results obtained by their use.

' In three comparable .si nqa nw'ed flies containing pyrethrum and with kerosene contain-- 7 ing 10% lauryl alcohol. The flies were kept under observation for 24'houi's. All of the fiiessprayed with kerosene recovered whereas the pyrethrum v 015fhovelinsecticidescan also be used in fly {sprays preferably in combination with petroleum hydrocarbons such as kerosene. Their toxic action on the common house-fly is very satisfactory.

' riments we have for inkerosene, with kerosene kerosene spray gave 60% mortality and the lau- :rylealcohol kerosenel spray gave 65% mortality.

.1; :The. outstanding advantage of our new insecticides is their higlr toxicity in low concentrations and their harmlessness to'plant life. We have. .found that lauryl compounds and derivatives are unique in this respect. In view of the fact that "ethyl alcohol can be applied in 100% concentration to aphids without giving completemontrol, it

is surprising that lauryl alcoholgives excellent control at 0.2% concentration. 7

Similarly other long carbon chain alcohols and .siticidal ingredient a-lauryl ester.

3. A parasiticide comprising as the active para- -non-metallic element included in groups V, VI and their derivatives have only a very mild toxic ef= feet towards insects and other lower forms of life. 7

We found, for instance, that primary or secondary alcohols or their derivatives containing carbon chains of less than 12 or more than 12 carbon atoms are considerably less eflective than .lauryl alcohol or its derivatives- Thus, for instance, while potassium lauryl xanthate at 0.2% concentration with sulfonated fish oil gave a 99-100% control on aphids, the control with potassium stearyl xanthate was only 35-40%. 7

We also found that mixtures ofalcohols containing from to 13 carbon atoms consisting mainly of secondary alcohols as produced from unsaturated petroleum hydrocarbons have very low toxicity toward lower forms of life, such as fungi and insects.

We claim: V 1. A 'parasiticidal composition comprising as the active parasiticidal ingredient a substance selected from the group of substances consisting of lauryl alcohol, lauryl esters and lauryl amines;

2. A parasiticide'comprising as an active parasiticidal ingredient a lauryl ester. of an organic acid.

4. A parasiticide comprising as the active parasiticidal ingredient a lauryl xanthate. V

5. A parasiticide comprising as the active parasiticidal ingredient a compound containing a straight chain of 12 carbon atoms in which one of the and atoms carries hydrogen and anegative, non-metallic atom.

. 6. A parasiticide comprising as the active parasiticidal ingredient a compound containing straight chain of 12 carbon atoms in which one of'the end carbon atoms carries hydrogenand a VII of the periodic systemof elements;

7. A parasiticide comprising asthe active parasiticidal ingredient a lauryl ester of aninorganic acid. 7

EUCLID W. BOUSQUET. GEORGE D. GRAVES. PAUL L. vSA'II'nZBIiiRCit 

